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This special issue of JCM ‘The Prevention and Treatment of Atherosclerosis’ will walk the Readers across novel diagnostic achievements in atherosclerosis and contemporary actions towards optimizing therapy.Everything begins with diagnosis. Accurate diagnostic tools and tests are of utmost importance. Contemporary research on microparticles, non-coding RNAs, proteomic characterization, …, offers detailed molecular characteristics of athero-thrombosis.Prevention is equally important as treatment. The impact of eating habits in prophylaxis of many pathologies, including cardiovascular disease has been documented.Then new pharmacological agents. Managing hypercholesterolemia with PCSK9 inhibitors, shown great potential in efficient lipid lowering to achieve LDL-C treatment goals, as well as reduction in cardiovascular mortality and morbidity.However, therapeutic goals accomplishment requires supervision. Arising number of data support that cardiovascular risk prediction can be improved with imaging modalities displaying atheroma: carotid plaque ultrasonography, coronary calcium score, intravascular ultrasonography, and optical coherent tomography or many others.As atherosclerosis is a progressive disease, it comes the time for more radical management, including endovascular and surgical intervention. There is field for new stent and equipment technologies, new surgical and endovascular techniques, supervision of endovascular procedures with IVUS, OCT, functional flow assessment or cell therapy.From diagnosis to risk stratification, elaborated prevention models, finally to modern and optimized therapeutic intervention.

familial hypercholesterolemia --- genetic screening --- atherosclerosis prevention --- early detection --- atherosclerosis --- cigarette smoking --- miR-27b --- peripheral artery disease --- subclinical atherosclerosis --- SCORE --- Framingham --- QRISK --- PROCAM --- cardiovascular risk --- pulse wave velocity --- intima media thickness --- malondialdehyde low-density lipoprotein --- high-risk plaque --- coronary computed tomography angiography --- statin --- cardiovascular risk factors --- heart failure --- major cardiac and cerebral ischemic events --- degenerative aortic stenosis --- risk stratification --- vascular resistance --- cardiovascular disease --- acute myocardial infarction --- intravascular imaging --- statins --- control-theoretic model --- logistic growth --- coronary artery disease --- fibrin clot --- fibrinolysis --- thromboembolism --- carotid intima-media complex --- carotid plaque --- major adverse cardiac and cerebral events --- prevention --- scores --- vitamin D --- myocardial infarction --- males --- Coronary Artery Surgery Study Score --- n/a

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To meet the global food demand of an increasing population, food production has to be increased by 60% by 2050. The main production constraints, such as climate change, biotic stresses, abiotic stresses, soil nutrition deficiency problems, problematic soils, etc., have to be addressed on an urgent basis. More than 50% of human calories are from three major cereals: rice, wheat, and maize. The harnessing of genetic diversity by novel allele mining assisted by recent advances in biotechnological and bioinformatics tools will enhance the utilization of the hidden treasures in the gene bank. Technological advances in plant breeding will provide some solutions for the biofortification, stress resistance, yield potential, and quality improvement in staple crops. The elucidation of the genetic, physiological, and molecular basis of useful traits and the improvement of the improved donors containing multiple traits are key activities for variety development. High-throughput genotyping systems assisted by bioinformatics and data science provide efficient and easy tools for geneticists and breeders. Recently, new breeding techniques applied in some food crops have become game-changers in the global food crop market. With this background, we invited 18 eminent researchers working on food crops from across the world to contribute their high-quality original research manuscripts. The research studies covered modern food crop genetics and breeding.

dry direct-seeded rice --- early vigor --- QTL --- candidate gene --- phenotyping --- EMS --- MutMap --- mutagenesis --- CLE7 --- tropical maize --- fasciation --- mapping --- radish --- microspore culture --- regeneration rate --- outcrossing --- two-way pseudo-testcross model --- Oryza sativa L. --- PPDK --- flo4-5 --- floury endosperm --- rice --- allelopathy --- yield --- HYV --- Tongil --- indica --- japonica --- SNP --- molecular breeding --- wheat quality --- wheat milling --- wheat hardness --- puroindolines --- water absorption capacity --- crop genetics --- Solanum tuberosum --- abiotic stress --- phenylpropanoids --- essential amino acid --- transcriptome --- small RNA --- comparative genomics --- nutrition --- days to heading --- Hd1 --- Ghd7 --- Hd16 --- chromosome segment substitution lines (CSSLs) --- quantitative trait locus (QTL) --- marker-assisted selection (MAS) --- cold tolerance (CT) --- gene editing --- genetically modified --- genetically modified organism (GMO) --- crop breeding --- ribonucleoprotein complex (RNP) --- genetic screening --- landraces --- genetic diversity --- population structure --- West Africa --- maize improvement --- DArTseq markers --- co-expression network --- drought-tolerant-yield --- reproductive-stage drought --- qDTYs --- transcriptomics --- watermelon --- pentatricopeptide-repeat (PPR) gene family --- comprehensive analysis --- expression profiling --- flesh color --- canola --- Brassica napus --- genetics --- gene technology --- genomics --- disease resistance --- CSSLs --- drought stress --- ‘KDML105’ rice --- low-temperature germinability --- interspecific cross --- interaction --- peanut --- core collection --- genome-wide association study --- linkage disequilibrium